After downloading the .ipynb notebook file from D2L you should move (not copy) it to the directory you’ll be working from.  But this leads to another issue: you need to start Jupyter in a directory above that directory so that Jupyter can access it.

 

Here’s what I suggest you do in the lab:

 

Click on the floppy disk icon periodically to save changes to your notebook.

When you're finished, use the menu item "File -> Close and Halt" to stop the background server process and close the browser window.

Upload the .ipynb file to the correct dropbox.  Check the timestamp on the file (on the disk) to make sure you're uploading the modified version, not the version you downloaded.